Metabolic responsiveness to training depends on insulin sensitivity and protein content of exosomes in insulin-resistant males

Author:

Apostolopoulou Maria123ORCID,Mastrototaro Lucia23ORCID,Hartwig Sonja34ORCID,Pesta Dominik23ORCID,Straßburger Klaus35ORCID,de Filippo Elisabetta23,Jelenik Tomas23ORCID,Karusheva Yanislava23ORCID,Gancheva Sofiya123,Markgraf Daniel23ORCID,Herder Christian123ORCID,Nair K. Sreekumaran6ORCID,Reichert Andreas S.7ORCID,Lehr Stefan34ORCID,Müssig Karsten123,Al-Hasani Hadi34,Szendroedi Julia1238ORCID,Roden Michael123ORCID

Affiliation:

1. Department of Endocrinology and Diabetology, Medical Faculty and University Hospital, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

2. Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

3. German Center for Diabetes Research, Partner Düsseldorf, München-Neuherberg, Germany.

4. Institute for Clinical Biochemistry and Pathobiochemistry German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

5. Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

6. Division of Endocrinology, Diabetes and Nutrition, Mayo Clinic, Rochester, MN, USA.

7. Institute of Biochemistry and Molecular Biology I, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

8. Department of Internal Medicine, Heidelberg University, Heidelberg, Germany.

Abstract

SEV may serve as new biomarkers for predicting the individual response of insulin sensitivity to exercising.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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