Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder

Author:

Lacerda Mariano Livia12ORCID,Rousseau Matthieu12ORCID,Varet Hugo34ORCID,Legendre Rachel34ORCID,Gentek Rebecca5ORCID,Saenz Coronilla Javier6,Bajenoff Marc5,Gomez Perdiguero Elisa6ORCID,Ingersoll Molly A.12ORCID

Affiliation:

1. Department of Immunology, Institut Pasteur, 75015 Paris, France.

2. INSERM U1223 Paris, France.

3. Bioinformatic and Biostatistic Hub, Department of Computational Biology, Institut Pasteur, USR 3756 CNRS, Paris, France.

4. Biomics Platform, Center for Technological Resources and Research (C2RT), Institut Pasteur, Paris, France.

5. Aix Marseille University, CNRS, INSERM, CIML, Marseille, France.

6. Macrophages and Endothelial Cells, Department of Developmental and Stem Cell Biology, CNRS UMR3738, Department of Immunology, Institut Pasteur, Paris, France.

Abstract

Phenotypically and spatially distinct macrophage subsets reside in the bladder with differing roles in response to infection.

Funder

Horizon 2020 Framework Programme

Agence Nationale de la Recherche

Fondation Schlumberger pour l’Education et la Recherche

Emergence(s) program from Ville de Paris

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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