R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage-Reference-Cited by-同舟云学术

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R-loops trigger the release of cytoplasmic ssDNAs leading to chronic inflammation upon DNA damage

Published:2021-11-19 Issue:47 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Chatzidoukaki Ourania¹²^ORCID,Stratigi Kalliopi¹^ORCID,Goulielmaki Evi¹,Niotis George¹³^ORCID,Akalestou-Clocher Alexia¹³,Gkirtzimanaki Katerina¹^ORCID,Zafeiropoulos Alexandros²,Altmüller Janine⁴^ORCID,Topalis Pantelis¹^ORCID,Garinis George A.¹³^ORCID

Affiliation:

1. Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013 Heraklion, Crete, Greece.

2. Medical School, University of Crete, Heraklion, Crete, Greece.

3. Department of Biology, University of Crete, Heraklion, Crete, Greece.

4. Cologne Center for Genomics (CCG), Institute for Genetics, University of Cologne, 50931 Cologne, Germany.

Abstract

R-loops lead to chronic inflammation upon DNA damage.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference61 articles.

1. DNA Damage Response and Metabolic Reprogramming in Health and Disease

2. Molecular pathology of rare progeroid diseases

3. The central role of DNA damage in the ageing process

4. Nucleotide Excision Repair and Transcription‐Associated Genome Instability

5. Nucleotide excision repair: new tricks with old bricks

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1. TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival;Cell;2024-09

2. R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells;Cellular and Molecular Life Sciences;2024-08-09

3. Broken strands, broken minds: Exploring the nexus of DNA damage and neurodegeneration;DNA Repair;2024-08

4. Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA;Science Immunology;2024-06-14

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