Protein detection in blood with single-molecule imaging

Author:

Mao Chih-Ping12ORCID,Wang Shih-Chin3ORCID,Su Yu-Pin4,Tseng Ssu-Hsueh5,He Liangmei6,Wu Annie A.6ORCID,Roden Richard B. S.567ORCID,Xiao Jie3ORCID,Hung Chien-Fu567ORCID

Affiliation:

1. Department of Pathology, Brigham and Women’s Hospital, Boston, MA, USA.

2. Harvard Medical School, Boston, MA, USA.

3. Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

4. Lieber Institute for Brain Development, Baltimore, MD, USA.

5. Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

6. Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

7. Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore MD, USA.

Abstract

A single-molecule imaging approach detects individual disease-specific protein molecules in blood samples.

Funder

National Institutes of Health

National Cancer Institute, Cairo University

Johns Hopkins University Discovery Award

The Hamilton Innovation Award

Taiwanese Government Scholarship

National Institutes of Health Medical Scientist Training Program Award

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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