Streptavidin-conjugated gold nanoclusters as ultrasensitive fluorescent sensors for early diagnosis of HIV infection

Author:

Kurdekar Aditya Dileep1,Avinash Chunduri L. A.2,Manohar C. Sai3ORCID,Haleyurgirisetty Mohan Kumar4ORCID,Hewlett Indira K.4,Venkataramaniah Kamisetti1

Affiliation:

1. Laboratories for Nanoscience and Nanotechnology Research, Department of Physics, Sri Sathya Sai Institute of Higher Learning, Prasanthinilayam, Andhra Pradesh, India.

2. Andhra Med Tech Zone, Hill No. 2, IT Park Madhurwada, Rushikonda, Vishakhapatnam, Andhra Pradesh 530045, India.

3. Department of Chemistry, Sri Sathya Sai Institute of Higher Learning, Prasanthinilayam, India.

4. Laboratory of Molecular Virology, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20993, USA.

Abstract

GNCIA allows a sensitive and selective detection of HIV-1 infections with a sensitivity of 5 pg/ml.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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