PET, image-guided HDAC inhibition of pediatric diffuse midline glioma improves survival in murine models-Reference-Cited by-同舟云学术

PET, image-guided HDAC inhibition of pediatric diffuse midline glioma improves survival in murine models

Published:2020-07-24 Issue:30 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Tosi Umberto¹^ORCID,Kommidi Harikrishna²^ORCID,Adeuyan Oluwaseyi¹,Guo Hua²,Maachani Uday Bhanu¹,Chen Nandi²,Su Taojunfeng³,Zhang Guoan³,Pisapia David J.⁴,Dahmane Nadia¹,Ting Richard²^ORCID,Souweidane Mark M.¹⁵^ORCID

Affiliation:

1. Department of Neurological Surgery, Weill Cornell Medicine, New York, NY 10065, USA.

2. Department of Radiology, Molecular Imaging Innovations Institute, Weill Cornell Medicine, New York, NY 10065, USA.

3. Proteomics and Metabolomics Core Facility, Weill Cornell Medicine, New York, NY 10021, USA.

4. Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA.

5. Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Abstract

In vivo, real-time image-guided CED of a PET-imageable HDAC inhibitor is needed to improve survival in murine models of DIPG.

Funder

U.S. Department of Defense

Alex’s Lemonade Stand Foundation for Childhood Cancer

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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