Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation-Reference-Cited by-同舟云学术

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Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation

Published:2020-05 Issue:18 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Prosseda Philipp P.¹^ORCID,Alvarado Jorge A.¹^ORCID,Wang Biao¹,Kowal Tia J.¹^ORCID,Ning Ke¹^ORCID,Stamer W. Daniel²^ORCID,Hu Yang¹,Sun Yang¹³^ORCID

Affiliation:

1. Department of Ophthalmology, Stanford University School of Medicine, 1651 Page Mill Road, Rm 2220, Palo Alto, CA 94305, USA.

2. Duke Eye Center, Department of Ophthalmology, Duke University, Durham, NC 27710, USA.

3. Palo Alto Veterans Administration, Palo Alto, CA 94304, USA.

Abstract

An optogenetic approach targeting phospholipids regulates eye pressure in mice with glaucoma.

Funder

NIH Office of the Director

U.S. Department of Veterans Affairs

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference44 articles.

1. Open-Angle Glaucoma

2. Current understanding of conventional outflow dysfunction in glaucoma

3. TGFβ2 Induces the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells Through the Smad and Non-Smad Dependent Pathways

4. Regulation of Trabecular Meshwork Cell Contraction and Intraocular Pressure by miR-200c

5. Aqueous outflow - A continuum from trabecular meshwork to episcleral veins

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