The surface stress of biomedical silicones is a stimulant of cellular response

Author:

Cheng Zhu1ORCID,Shurer Carolyn R.1ORCID,Schmidt Samuel12ORCID,Gupta Vivek K.34,Chuang Grace1ORCID,Su Jin5,Watkins Amanda R.5,Shetty Abhishek6,Spector Jason A.7ORCID,Hui Chung-Yuen38,Reesink Heidi L.5ORCID,Paszek Matthew J.12910ORCID

Affiliation:

1. Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.

2. Kavli Institute at Cornell for Nanoscale Science, Ithaca, NY 14853, USA.

3. Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA.

4. Department of Mechanical Engineering, Stanford University, CA 94305, USA.

5. College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

6. Rheology Department, Anton Paar USA Inc., Ashland, VA 23005, USA.

7. Weill Cornell Medicine, Cornell University, New York, NY 10065, USA.

8. Field of Theoretical and Applied Mechanics, Cornell University, Ithaca, NY 14853, USA.

9. Field of Biophysics, Cornell University, Ithaca, NY 14853, USA.

10. Field of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA.

Abstract

Cells feel the tension of implanted and injected silicone materials.

Funder

National Science Foundation

National Institutes of Health

National Cancer Institute

National Institute of General Medical Sciences

US Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering Sciences

Samuel C. Fleming Family Graduate Fellowship

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Knight Family Foundation Graduate Research Fellowship in Nanoscience and Technology

Kavli Institute at Cornell Postdoctoral fellowship

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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