Memory enhancement by ferulic acid ester across species

Author:

Michels Birgit1ORCID,Zwaka Hanna12ORCID,Bartels Ruth2ORCID,Lushchak Oleh3ORCID,Franke Katrin4,Endres Thomas5ORCID,Fendt Markus67ORCID,Song Inseon8ORCID,Bakr May8ORCID,Budragchaa Tuvshinjargal4,Westermann Bernhard4ORCID,Mishra Dushyant9,Eschbach Claire9,Schreyer Stefanie2,Lingnau Annika2,Vahl Caroline2ORCID,Hilker Marike2,Menzel Randolf2,Kähne Thilo10,Leßmann Volkmar57ORCID,Dityatev Alexander785ORCID,Wessjohann Ludger4ORCID,Gerber Bertram1711ORCID

Affiliation:

1. Leibniz Institute for Neurobiology, Department Genetics of Learning and Memory, Magdeburg, Germany.

2. Free University Berlin, Institute of Neurobiology, Berlin, Germany.

3. Precarpathian National University, Department of Biochemistry, Ivano-Frankivsk, Ukraine.

4. Leibniz Institute of Plant Biochemistry (IPB), Department of Bioorganic Chemistry, Halle (Saale), Germany.

5. Otto von Guericke University, Medical Faculty, Magdeburg, Germany.

6. Otto von Guericke University, Medical Faculty, Institute for Pharmacology and Toxicology, Magdeburg, Germany.

7. Center for Behavioral Brain Sciences (CBBS), Otto von Guericke University, Magdeburg, Germany.

8. German Center for Neurodegenerative Diseases (DZNE), Molecular Neuroplasticity Group, Magdeburg, Germany.

9. University of Würzburg, Biocenter Am Hubland, Department of Genetics and Neurobiology, Würzburg, Germany.

10. Otto von Guericke University, Institute of Experimental Internal Medicine, Magdeburg, Germany.

11. Otto von Guericke University, Institute of Biology, Magdeburg, Germany.

Abstract

Inspired from plant medicine, a drug that partially compensates for memory decline in aged flies and mice is identified.

Funder

European Commission

Leibniz Association

German Science Foundation

German Center for Neurodegenerative Diseases

Otto-von-Guericke-University Magdeburg

Leibniz Institute for Neurobiology Magdeburg

German Federal Ministry of Science and Technology

BMBF and EU Horizon 2020

Leibniz Research Alliance Bioactive Compounds and Biotechnology

German-Israel Foundation

University of Wuerzburg

the company of biologists

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference74 articles.

1. Rhodiola rosea. A phytomedicinal overview;Brown R. P.;HerbalGram,2002

2. C. Linnaeus Materia medica. Liber I De plantis (Lars Salvius 1749) p. 168.

3. Rosenroot (Rhodiola rosea): Traditional use, chemical composition, pharmacology and clinical efficacy;Panossian A.;Phytomedicine,2010

4. European Medicines Agency Assessment report on Rhodiola rosea L. rhizoma et radix (London United Kingdom 2012); www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2012/05/WC500127861.pdf.

5. National Institutes of Health Rhodiola (National Center for Complementary and Integrative Health 2016); https://nccih.nih.gov/health/rhodiola.

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