A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery-Reference-Cited by-同舟云学术

A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery

Published:2021-09-03 Issue:36 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Choi Yun-Rak¹²³⁴^ORCID,Collins Kelsey H.¹²³^ORCID,Springer Luke E.⁵^ORCID,Pferdehirt Lara¹²³⁶^ORCID,Ross Alison K.¹²³⁶^ORCID,Wu Chia-Lung¹²³^ORCID,Moutos Franklin T.⁷,Harasymowicz Natalia S.¹²³^ORCID,Brunger Jonathan M.⁸⁹^ORCID,Pham Christine T. N.⁵^ORCID,Guilak Farshid¹²³⁶⁷^ORCID

Affiliation:

1. Department of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO 63110, USA.

2. Shriners Hospitals for Children, St. Louis, MO 63110, USA.

3. Center of Regenerative Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.

4. Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, South Korea.

5. Division of Rheumatology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.

6. Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA.

7. Cytex Therapeutics Inc., Durham, NC 27704, USA.

8. Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235, USA.

9. Center for Stem Cell Biology, Vanderbilt University, Nashville, TN 37235, USA.

Abstract

Genome editing of stem cells creates a living implant that can produce arthritis-fighting drugs in response to inflammation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference45 articles.

1. Non–TNF-Targeted Biologic vs a Second Anti-TNF Drug to Treat Rheumatoid Arthritis in Patients With Insufficient Response to a First Anti-TNF Drug

2. Risk of serious adverse effects of biological and targeted drugs in patients with rheumatoid arthritis: A systematic review meta-analysis;Tarp S.;Rheumatology,2017

3. Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs

4. Self-adjusting synthetic gene circuit for correcting insulin resistance

5. Towards an arthritis flare-responsive drug delivery system

Cited by 26 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tuning the Response of Synthetic Mechanogenetic Gene Circuits Using Mutations in TRPV4;Tissue Engineering Part A;2024-08-02

2. Advanced material technologies for space and terrestrial medicine;Nature Reviews Materials;2024-06-03

3. Engineered Self-Regulating Macrophages for Targeted Anti-inflammatory Drug Delivery;2024-05-31

4. Emerging technology has a brilliant future: the CRISPR-Cas system for senescence, inflammation, and cartilage repair in osteoarthritis;Cellular & Molecular Biology Letters;2024-05-02

5. The evolving landscape of gene therapy strategies for the treatment of osteoarthritis;Osteoarthritis and Cartilage;2024-04