ECM-inspired micro/nanofibers for modulating cell function and tissue generation

Author:

Xu Yun12ORCID,Shi Guodong2ORCID,Tang Jincheng1ORCID,Cheng Ruoyu3ORCID,Shen Xiaofeng4ORCID,Gu Yong1ORCID,Wu Liang1ORCID,Xi Kun1ORCID,Zhao Yihong2ORCID,Cui Wenguo13ORCID,Chen Liang1ORCID

Affiliation:

1. Department of Orthopedics, The First Affiliated Hospital of Soochow University, Orthopedic Institute, Soochow University, 708 Renmin Road, Suzhou, Jiangsu 215006, P.R. China.

2. Departments of Pain Rehabilitation and Orthopaedic Surgery, Shanghai Public Health Clinical Center, Fudan University, 2901 Caolang Road, Shanghai 201500, P.R. China.

3. Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Second Road, Shanghai 200025, P.R. China.

4. Department of Orthopaedic Surgery, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, 889 Wuzhong West Road, Suzhou, Jiangsu 215006, P.R. China.

Abstract

A ECM-inspired heterogeneous scaffold promoted dura mater healing and inhibited fibrosis via microstructural/biochemical cues.

Funder

National Natural Science Foundation of China

Science and Technology Commission of Shanghai Municipality

Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support

National Key Research Project

Shanghai Jinshan district science and technology committee, medical and health science and technology innovation fund project

Shanghai public health clinical center, Fudan university,the academy project

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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