Depolarizing GABA A current in the prefrontal cortex is linked with cognitive impairment in a mouse model relevant for schizophrenia-Reference-Cited by-同舟云学术

Depolarizing GABA A current in the prefrontal cortex is linked with cognitive impairment in a mouse model relevant for schizophrenia

Author:

Kim Haram R.¹^ORCID,Rajagopal Lakshmi²^ORCID,Meltzer Herbert Y.¹²^ORCID,Martina Marco¹²^ORCID

Affiliation:

1. Department of Physiology, Feinberg School of Medicine, Northwestern University, 300 E. Chicago Avenue, Chicago, IL 60611, USA.

2. Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, 300 E. Chicago Avenue, Chicago, IL 60611, USA.

Abstract

Cognitive deficit in a rodent model of schizophrenia is linked to cortical depolarizing GABA current due to NKCC1 overexpression.

Funder

NIH/NINDS

NIH/NIDA

NIH/NIMH

Weisman family

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference54 articles.

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