Human TRA2A determines influenza A virus host adaptation by regulating viral mRNA splicing

Author:

Zhu Yinxing12ORCID,Wang Ruifang12,Yu Luyao12,Sun Huimin12,Tian Shan12,Li Peng12,Jin Meilin12,Chen Huanchun12ORCID,Ma Wenjun3,Zhou Hongbo12ORCID

Affiliation:

1. State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.

2. Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Cooperative Innovation Center for Sustainable Pig Production, Wuhan 430070, China.

3. Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, USA.

Abstract

The human host factor TRA2A plays an important role in cross-species transmission of avian influenza virus.

Funder

National Natural Science Foundation of China

The National Key Research and Development Program of China

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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