FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity-Reference-Cited by-同舟云学术

FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity

Author:

Ren Jun¹²^ORCID,Sun Mingming¹³^ORCID,Zhou Hao³⁴^ORCID,Ajoolabady Amir³⁵^ORCID,Zhou Yuan⁶^ORCID,Tao Jun⁷,Sowers James R.⁸,Zhang Yingmei¹^ORCID

Affiliation:

1. Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

2. Department of Pathology, University of Washington Seattle, Seattle, WA 98195, USA.

3. University of Wyoming College of Health Sciences, Laramie, WY 82071, USA.

4. Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing 100853, China.

5. Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz 5185715179, Iran.

6. Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing 100191, China.

7. Department of Cardiovascular Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510000, China.

8. Diabetes and Cardiovascular Research Center, University of Missouri Columbia, Columbia, MO 65212, USA.

Abstract

The mitophagy receptor FUNDC1 interacts with FBXL2 to preserve mitochondrial Ca 2+ homeostasis and cardiac function in obesity.

Funder

National Natural Science Foundation of China

Chinese Academy of Medical Sciences

National Key Research and Development Program of China Stem Cell and Translational Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference47 articles.

Cited by 107 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献