Cross-talk between CDK4/6 and SMYD2 regulates gene transcription, tubulin methylation, and ciliogenesis-Reference-Cited by-同舟云学术

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Cross-talk between CDK4/6 and SMYD2 regulates gene transcription, tubulin methylation, and ciliogenesis

Published:2020-10-30 Issue:44 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Li Linda Xiaoyan¹²^ORCID,Zhou Julie Xia¹²,Wang Xiaodong³^ORCID,Zhang Hongbing¹²^ORCID,Harris Peter C.¹²,Calvet James P.³,Li Xiaogang¹²^ORCID

Affiliation:

1. Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.

2. Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.

3. Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Abstract

CDK4 and CDK6 regulate ciliogenesis and Hedgehog signaling via their novel substrate SMYD2.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference40 articles.

1. Targeting CDK4 and CDK6: From Discovery to Therapy

2. Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

3. Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

4. A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells

5. Primary Cilia and the Cell Cycle

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1. SMYD3 Controls Ciliogenesis by Regulating Distinct Centrosomal Proteins and Intraflagellar Transport Trafficking;International Journal of Molecular Sciences;2024-05-30

2. The effects of immortalization on the N-glycome and proteome of CDK4-transformed lung cancer cells;Glycobiology;2024-04-05

3. Overexpression of SMYD3 Promotes Autosomal Dominant Polycystic Kidney Disease by Mediating Cell Proliferation and Genome Instability;Biomedicines;2024-03-07

4. Morphological Changes of 3T3 Cells under Simulated Microgravity;Cells;2024-02-15

5. Strategy of combining CDK4/6 inhibitors with other therapies and mechanisms of resistance;International Journal of Clinical and Experimental Pathology;2024

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