The unconventional biogenesis of Kv7.1-KCNE1 complexes-Reference-Cited by-同舟云学术

The unconventional biogenesis of Kv7.1-KCNE1 complexes

Published:2020-04-03 Issue:14 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Oliveras Anna¹^ORCID,Serrano-Novillo Clara¹^ORCID,Moreno Cristina²,de la Cruz Alicia³^ORCID,Valenzuela Carmen³⁴^ORCID,Soeller Christian⁵^ORCID,Comes Núria⁶,Felipe Antonio¹^ORCID

Affiliation:

1. Molecular Physiology Laboratory, Departamento de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.

2. National Institute of Neurological Disorders and Stroke (NIH), Bethesda, MD, USA.

3. Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.

4. Spanish Network for Biomedical Research in Cardiovascular Research (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.

5. Living Systems Institute and Biomedical Physics, University of Exeter, Exeter, UK.

6. Departamento De Biomedicina, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

Abstract

The cardiac I Ks (Kv7.1-KCNE1) channel assembles at ER-PM junctions before translocated to the plasma membrane.

Funder

Ministerio de Economía y Competitividad

Instituto de Salud Carlos III

European Regional Development Fund

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference41 articles.

1. KCNQ potassium channels: physiology, pathophysiology, and pharmacology

2. Kv7.1 (KCNQ1) properties and channelopathies

3. KvLQT1 and IsK (minK) proteins associate to form the IKS cardiac potassium current

4. Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel

5. A personalized approach to long QT syndrome

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