Mechanism of C-type inactivation in the hERG potassium channel-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Mechanism of C-type inactivation in the hERG potassium channel

Published:2021-01-29 Issue:5 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Li Jing¹^ORCID,Shen Rong²^ORCID,Reddy Bharat²^ORCID,Perozo Eduardo²^ORCID,Roux Benoît²^ORCID

Affiliation:

1. Department of BioMolecular Sciences, Division of Medicinal Chemistry, School of Pharmacy, University of Mississippi, University, MS 38677, USA.

2. Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.

Abstract

C-type inactivation in hERG is associated with an asymmetrical constricted-like conformation of the selectivity filter.

Funder

National Science Foundation

Foundation for the National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference59 articles.

1. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

2. hERG potassium channels and cardiac arrhythmia

3. A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

4. The inward rectification mechanism of the HERG cardiac potassium channel

5. HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Potassium dependent structural changes in the selectivity filter of HERG potassium channels;Nature Communications;2024-08-29

2. Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting;2024-05-28

3. Honeybee CaV4 has distinct permeation, inactivation, and pharmacology from homologous NaV channels;Journal of General Physiology;2024-04-01

4. The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue;FEBS Letters;2024-04

5. Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations;2024-03-15

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3