Integrin-mediated adhesions in regulation of cellular senescence

Author:

Shin Eun-Young1ORCID,Park Jin-Hee1,You Soon-Tae1ORCID,Lee Chan-Soo2,Won So-Yoon1ORCID,Park Jung-Jin1,Kim Han-Byeol1,Shim Jaegal3,Soung Nak-Kyun4,Lee Ok-Jun5,Schwartz Martin Alexander67ORCID,Kim Eung-Gook1ORCID

Affiliation:

1. Department of Biochemistry, Chungbuk National University College of Medicine, Cheongju 28644, Korea.

2. Food Standard Division Scientific Office, Ministry of Food and Drug Safety (KFDA), Osong-eup, Cheongju 28159, Korea.

3. Comparative Biomedicine Research Branch, Research Institute, National Cancer Center, Goyang 10408, Korea.

4. World Class Institute, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang-eup, Cheongju 28116, Korea.

5. Department of Pathology, Chungbuk National University College of Medicine, Cheongju 28644, Korea.

6. Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine and Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06511, USA.

7. Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester, UK.

Abstract

βPIX and GIT control cellular senescence through integrin signaling.

Funder

National Research Foundation of Korea

United States Public Health Service

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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