Molecular Interaction Maps--A Diagrammatic Graphical Language for Bioregulatory Networks-Reference-Cited by-同舟云学术

Molecular Interaction Maps--A Diagrammatic Graphical Language for Bioregulatory Networks

Published:2004-03-02 Issue:222 Volume:2004 Page:
ISSN:1525-8882
Container-title:Science's STKE
language:en
Short-container-title:Sci. STKE

Author:

Aladjem Mirit I.¹,Pasa Stefania²,Parodi Silvio²,Weinstein John N.¹,Pommier Yves¹,Kohn Kurt W.¹

Affiliation:

1. Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

2. Laboratory of Experimental Oncology, National Institute of Cancer Research and University of Genoa, Genoa, Italy.

Abstract

Molecular interaction maps (MIMs) use a clear, accurate, and versatile graphical language to depict complex biological processes. Here, we discuss the main features of the MIM language and its potential uses. MIMs can be used as database resources and simulation guides, and can serve to generate new hypotheses regarding the roles of specific molecules in the bioregulatory networks that control progression through the cell cycle, differentiation, and cell death.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference20 articles.

1. Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems

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5. Molecular Interaction Maps (http://discover.nci.nih.gov/mim).

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