Single-cell analysis pinpoints distinct populations of cytotoxic CD4 + T cells and an IL-10 + CD109 + T H 2 cell population in nasal polyps-Reference-Cited by-同舟云学术

Single-cell analysis pinpoints distinct populations of cytotoxic CD4 + T cells and an IL-10 + CD109 + T H 2 cell population in nasal polyps

Published:2021-08-10 Issue:62 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Ma Junjie¹^ORCID,Tibbitt Christopher A.¹^ORCID,Georén Susanna Kumlien²³,Christian Murray¹^ORCID,Murrell Ben¹,Cardell Lars-Olaf²³^ORCID,Bachert Claus²⁴⁵^ORCID,Coquet Jonathan M.¹^ORCID

Affiliation:

1. Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, Sweden.

2. Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.

3. Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.

4. Upper Airways Research Laboratory and Department of Oto-Rhino-Laryngology, Ghent University, Ghent, Belgium.

5. First Affiliated Hospital, Sun Yat-sen University, International Airway Research Center, Guangzhou, China.

Abstract

Transcriptional profiling pinpoints the heterogeneity of T helper cells in human nasal polyps at the clonal level.

Funder

Cancerfonden

Vetenskapsrådet

Konsul Bergh

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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