Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium-Reference-Cited by-同舟云学术

Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium

Published:2021-11-26 Issue:65 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Wang Jiaxi¹^ORCID,Lareau Caleb A.²³^ORCID,Bautista Jhoanne L.⁴,Gupta Alexander R.¹⁴^ORCID,Sandor Katalin²^ORCID,Germino Joe¹,Yin Yajie²^ORCID,Arvedson Matthew P.¹,Reeder Gabriella C.¹^ORCID,Cramer Nathan T.¹,Xie Fang¹⁴,Ntranos Vasilis¹⁵^ORCID,Satpathy Ansuman T.²³^ORCID,Anderson Mark S.¹⁶^ORCID,Gardner James M.¹⁴^ORCID

Affiliation:

1. Diabetes Center, University of California San Francisco, San Francisco, CA, USA.

2. Department of Pathology, Stanford University, Stanford, CA, USA.

3. Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA.

4. Department of Surgery, University of California San Francisco, San Francisco, CA, USA.

5. Department of Epidemiology and Biostatistics, Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.

6. Department of Medicine, University of California San Francisco, San Francisco, CA, USA.

Abstract

Extrathymic Aire-expressing cells are hematopoietic migratory DC–like populations with homology to medullary thymic epithelium.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference62 articles.

1. Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

2. The Cellular Mechanism of Aire Control of T Cell Tolerance

3. Increased antigen presenting cell-mediated T cell activation in mice and patients without the autoimmune regulator

4. Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells

5. Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

Cited by 46 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The renaissance of oral tolerance: merging tradition and new insights;Nature Reviews Immunology;2024-09-06

2. Coordinated network of T cells and antigen presenting cells regulate tolerance to food;2024-07-16

3. Aire in Autoimmunity;Annual Review of Immunology;2024-06-28

4. Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues;2024-05-10

5. Early life microbiome influences on development of the mucosal innate immune system;Seminars in Immunology;2024-05