IL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response-Reference-Cited by-同舟云学术

IL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response

Published:2019-06-07 Issue:36 Volume:4 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Bernshtein Biana¹^ORCID,Curato Caterina¹^ORCID,Ioannou Marianna²^ORCID,Thaiss Christoph A.¹,Gross-Vered Mor¹,Kolesnikov Masha¹,Wang Qian²^ORCID,David Eyal¹^ORCID,Chappell-Maor Louise¹^ORCID,Harmelin Alon³^ORCID,Elinav Eran¹^ORCID,Thakker Paresh⁴^ORCID,Papayannopoulos Venizelos²,Jung Steffen¹^ORCID

Affiliation:

1. Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.

2. Francis Crick Institute, London NW1 1AT, UK.

3. Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 76100, Israel.

4. Regeneron Pharmaceuticals, Inc., 777 Old Saw Mill River, Tarrytown, NY 10591, USA.

Abstract

Proinflammatory IL-10R–deficient colonic macrophages trigger defined T cell and epithelial responses causing colitis.

Funder

European Research Council

Era-Net Infect

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference63 articles.

1. Finding the missing heritability of complex diseases

2. Fine-mapping inflammatory bowel disease loci to single-variant resolution;Huang H.;Nature,2017

3. Diversity and functions of intestinal mononuclear phagocytes

4. Innate lymphoid cells in the initiation, regulation and resolution of inflammation

5. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis;Mortha A.;Science,2014

Cited by 74 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance;Immunity;2024-09

2. The role of macrophages in fibrosis of chronic kidney disease;Biomedicine & Pharmacotherapy;2024-08

3. OLFM4 modulates intestinal inflammation by promoting IL-22+ILC3 in the gut;Communications Biology;2024-07-29

4. IL-22, a vital cytokine in autoimmune diseases;Clinical and Experimental Immunology;2024-04-23

5. The crucial role of fish mucus in regulating progeny inflammation and microbial homeostasis;Water Biology and Security;2024-04