Gasdermin D plays a vital role in the generation of neutrophil extracellular traps-Reference-Cited by-同舟云学术

Gasdermin D plays a vital role in the generation of neutrophil extracellular traps

Published:2018-08-03 Issue:26 Volume:3 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Sollberger Gabriel¹,Choidas Axel²^ORCID,Burn Garth Lawrence¹^ORCID,Habenberger Peter²^ORCID,Di Lucrezia Raffaella²^ORCID,Kordes Susanne²^ORCID,Menninger Sascha²,Eickhoff Jan²^ORCID,Nussbaumer Peter²^ORCID,Klebl Bert²,Krüger Renate³,Herzig Alf¹,Zychlinsky Arturo¹

Affiliation:

1. Department of Cellular Microbiology, Max Planck Institute for Infection Biology, Charitéplatz 1, 10117 Berlin, Germany.

2. Lead Discovery Center GmbH, Otto-Hahn-Str. 15, Dortmund, Germany.

3. Charité—Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Department of Pediatric Pneumology, Immunology and Intensive Care, Berlin, Germany.

Abstract

By screening a library of compounds that block NETosis, we have identified a gasdermin D inhibitor.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference34 articles.

1. Beyond the grave: When is cell death critical for immunity to infection?

2. The Inflammasome

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