Affiliation:
1. School of Cancer Sciences, University of Glasgow, Glasgow G61 1BD, UK.
Abstract
The CCR7 receptor allows dendritic cells to sense the chemokine CCL19. It also depletes CCL19 from the environment by endocytosis, leading to local gradients that can steer cells accurately and robustly through tissues, even over long distances (see related Research Article by Alanko
et al
.).
Publisher
American Association for the Advancement of Science (AAAS)
Subject
General Medicine,Immunology