A reservoir of stem-like CD8 + T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response-Reference-Cited by-同舟云学术

A reservoir of stem-like CD8 + T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response

Published:2021-10-29 Issue:64 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Connolly Kelli A.¹^ORCID,Kuchroo Manik²^ORCID,Venkat Aarthi³^ORCID,Khatun Achia⁴,Wang Jiawei³^ORCID,William Ivana¹,Hornick Noah I.¹^ORCID,Fitzgerald Brittany L.¹,Damo Martina¹^ORCID,Kasmani Moujtaba Y.⁴^ORCID,Cui Can¹^ORCID,Fagerberg Eric¹^ORCID,Monroy Isabel¹^ORCID,Hutchins Amanda¹,Cheung Julie F.¹^ORCID,Foster Gena G.¹,Mariuzza Dylan L.¹^ORCID,Nader Mursal¹,Zhao Hongyu⁵^ORCID,Cui Weiguo⁴⁶,Krishnaswamy Smita⁷^ORCID,Joshi Nikhil S.¹^ORCID

Affiliation:

1. Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.

2. Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USA.

3. Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.

4. Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.

5. Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.

6. Versiti Blood Research Institute, Milwaukee, WI 53213, USA.

7. Department of Genetics and Computer Science, Yale University School of Medicine, New Haven, CT, USA.

Abstract

Tumor-specific CD8 + T cells in stable tumor-draining lymph node reservoir are clonally and developmentally related to those in tumors.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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