GAPs in early life facilitate immune tolerance-Reference-Cited by-同舟云学术

GAPs in early life facilitate immune tolerance

Published:2017-12-08 Issue:18 Volume:2 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Al Nabhani Ziad¹²^ORCID,Eberl Gérard¹²^ORCID

Affiliation:

1. Institut Pasteur, Microenvironment and Immunity Unit, 75724 Paris, France.

2. INSERM U1224, 75724 Paris, France.

Abstract

Goblet cells deliver microbial antigens to generate regulatory T cells before and during weaning to induce long-term tolerance to symbionts. See the related research article by Knoop et al.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference10 articles.

1. Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria

2. Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

3. The hygiene hypothesis in autoimmunity: The role of pathogens and commensals;Bach J.-F.;Nat. Rev. Immunol.,2017

4. Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

5. Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

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