Human “T H 9” cells are a subpopulation of PPAR-γ + T H 2 cells-Reference-Cited by-同舟云学术

Human “T H 9” cells are a subpopulation of PPAR-γ + T H 2 cells

Published:2019-01-04 Issue:31 Volume:4 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Micossé Claire¹^ORCID,von Meyenn Leonhard¹^ORCID,Steck Oliver¹,Kipfer Enja¹,Adam Christian²,Simillion Cedric³,Seyed Jafari S. Morteza¹^ORCID,Olah Peter⁴,Yawlkar Nikhil¹^ORCID,Simon Dagmar¹^ORCID,Borradori Luca¹,Kuchen Stefan⁵,Yerly Daniel⁵,Homey Bernhard⁴^ORCID,Conrad Curdin⁶^ORCID,Snijder Berend⁷^ORCID,Schmidt Marc²^ORCID,Schlapbach Christoph¹^ORCID

Affiliation:

1. Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

2. Department of Dermatology, University Hospital Würzburg, Würzburg, Germany.

3. Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland.

4. Department of Dermatology, University Hospital Düsseldorf, Düsseldorf, Germany.

5. Department of Rheumatology, Immunology and Allergology, Bern University Hospital, University of Bern, Bern, Switzerland.

6. Department of Dermatology, University Hospital CHUV, Lausanne, Switzerland.

7. Institute of Molecular Systems Biology, ETH, Zurich, Switzerland.

Abstract

The transcription factor PPAR-γ plays a vital role in the generation of IL-9–producing T H cells.

Funder

Swiss National Science Foundation

Peter Hans Hofschneider Professorship for Molecular Medicine

Promedica Foundation

Olga Mayenfisch Foundation

Novartis Foundation for biomedical research

Bernese League against Cancer

Hans Stettler Foundation

Berger Janser Foundation against Cancer

Inselspital CTU grants

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference44 articles.

1. Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity

2. Division of labour by CD4+ T helper cells

3. IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

4. Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

5. Modulation of Chromatin Structure Regulates Cytokine Gene Expression during T Cell Differentiation

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