A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses

Author:

Stary Victoria1ORCID,Pandey Ram Vinay2,Strobl Johanna2ORCID,Kleissl Lisa23ORCID,Starlinger Patrick14,Pereyra David15ORCID,Weninger Wolfgang2,Fischer Gottfried F.6ORCID,Bock Christoph78ORCID,Farlik Matthias2ORCID,Stary Georg237ORCID

Affiliation:

1. Department of Visceral Surgery, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

2. Department of Dermatology, Medical University of Vienna, Vienna, Austria.

3. Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.

4. Division of Hepatobiliary and Pancreas Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.

5. Center for Physiology and Pharmacology, Department of Thrombosis Research and Vascular Biology, Medical University of Vienna, Vienna, Austria.

6. Department of Blood Group Serology, University of Vienna, Vienna, Austria.

7. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

8. Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.

Abstract

CD49a + CD16 NK cells from the liver and contact dermatitis lesions specifically recognize antigens and contribute to adaptive immunity.

Funder

Austrian Academy of Sciences

Austrian Science Fund

Medical Scientific Fund of the Mayor of the City of Vienna

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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