B cells engineered to express pathogen-specific antibodies protect against infection-Reference-Cited by-同舟云学术

B cells engineered to express pathogen-specific antibodies protect against infection

Published:2019-05-24 Issue:35 Volume:4 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Moffett Howell F.¹^ORCID,Harms Carson K.¹^ORCID,Fitzpatrick Kristin S.¹^ORCID,Tooley Marti R.¹^ORCID,Boonyaratanakornkit Jim¹,Taylor Justin J.¹²³^ORCID

Affiliation:

1. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N. Seattle, WA 98109, USA.

2. Department of Global Health, University of Washington, 1510 San Juan Road, Seattle, WA 98195, USA.

3. Department of Immunology, University of Washington, 750 Republican St., Seattle, WA 98109, USA.

Abstract

B cells reprogrammed to express pathogen-specific antibodies using CRISPR-Cas9 protect against infection.

Funder

National Institutes of Health

The Hartwell Foundation

Vir Biotechnology

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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