Vaccine-driven lung TRM cells provide immunity against Klebsiella via fibroblast IL-17R signaling-Reference-Cited by-同舟云学术

Vaccine-driven lung TRM cells provide immunity against Klebsiella via fibroblast IL-17R signaling

Published:2021-09-24 Issue:63 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Iwanaga Naoki¹^ORCID,Chen Kong²,Yang Haoran¹^ORCID,Lu Shiping¹,Hoffmann Joseph P.¹^ORCID,Wanek Alanna¹,McCombs Janet E.¹^ORCID,Song Kejing¹,Rangel-Moreno Javier³^ORCID,Norton Elizabeth B.⁴,Kolls Jay K.¹^ORCID

Affiliation:

1. Departments of Pediatrics and Medicine, Center for Translational Research in Infection and Inflammation, Tulane University School of Medicine, New Orleans, LA 70112, USA.

2. Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.

3. Department of Medicine, University of Rochester, Rochester, NY 14642, USA.

4. Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

Abstract

A subunit mucosal vaccine conferred protection against heterologous Klebsiella pneumoniae strains, via IL-17R signaling in lung fibroblasts.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference53 articles.

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2. Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense