VpreB serves as an invariant surrogate antigen for selecting immunoglobulin antigen-binding sites-Reference-Cited by-同舟云学术

VpreB serves as an invariant surrogate antigen for selecting immunoglobulin antigen-binding sites

Author:

Khass Mohamed¹²,Blackburn Tessa³,Burrows Peter D.³,Walter Mark R.³,Capriotti Emidio⁴⁵,Schroeder Harry W.¹³

Affiliation:

1. Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

2. Division of Genetic Engineering, National Research Center of Egypt, Cairo, Egypt.

3. Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

4. Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

5. Institute for Mathematical Modeling of Biological Systems, Department of Biology, University of Düsseldorf, Düsseldorf, Germany.

Abstract

The VpreB component of the surrogate light chain serves as an invariant antigen that may affect the repertoire of antibody responses.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference27 articles.

3. Analysis of the antibody structure based on high-resolution crystallographic studies;Narciso J. E. T.;Nat. Biotechnol.,2011

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