Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation-Reference-Cited by-同舟云学术

Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation

Published:2021-07-29 Issue:61 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Calderón Lesly¹^ORCID,Schindler Karina¹^ORCID,Malin Stephen G.¹²^ORCID,Schebesta Alexandra¹^ORCID,Sun Qiong¹,Schwickert Tanja¹,Alberti Chiara¹^ORCID,Fischer Maria¹,Jaritz Markus¹^ORCID,Tagoh Hiromi¹^ORCID,Ebert Anja¹^ORCID,Minnich Martina¹^ORCID,Liston Adrian³^ORCID,Cochella Luisa¹^ORCID,Busslinger Meinrad¹^ORCID

Affiliation:

1. Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus-Vienna-Biocenter 1, A-1030 Vienna, Austria.

2. Laboratory of Immunobiology, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.

3. Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge CB22 3AT, UK.

Abstract

Pax5 controls the generation, proliferation, and survival of all mature B cells by promoting PI3K signaling via PTEN down-regulation.

Funder

H2020 European Research Council

Human Frontier Science Program

Osterreichische Forschungsforderungsgesellschaft

Osterreichische ForschungsfOrderungsgesellschaft

Austrian Industrial Research Promotion Agency Headquarter