A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands-Reference-Cited by-同舟云学术

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Published:2018-10-26 Issue:28 Volume:3 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Faridi Pouya¹^ORCID,Li Chen¹²^ORCID,Ramarathinam Sri H.¹^ORCID,Vivian Julian P.¹³^ORCID,Illing Patricia T.¹^ORCID,Mifsud Nicole A.¹^ORCID,Ayala Rochelle¹^ORCID,Song Jiangning¹⁴^ORCID,Gearing Linden J.⁵,Hertzog Paul J.⁵,Ternette Nicola⁶^ORCID,Rossjohn Jamie¹³⁷^ORCID,Croft Nathan P.¹^ORCID,Purcell Anthony W.¹^ORCID

Affiliation:

1. Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

2. Department of Biology, Institute of Molecular Systems Biology,ETH Zurich, Zurich 8093, Switzerland.

3. Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia.

4. Monash Centre for Data Science, Faculty of Information Technology, Monash University, Melbourne, Victoria 3800, Australia.

5. Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research and Department of Molecular and Translational Science, School of Clinical Science, Monash University, Clayton, Victoria 3168, Australia.

6. Jenner Institute, University of Oxford, Oxford OX3 7FZ, UK.

7. Institute of Infection and Immunity, Cardiff University School of Medicine,Heath Park, Cardiff CF14 4XN, UK.

Abstract

A considerable proportion of HLA-I peptides likely derive from cis- and trans-splicing events.

Funder

Australian Research Council

National Health and Medical Research Council

Faculty of Medicine, Nursing and Health Sciences, Monash University

National Institute of Allergy and Infectious Diseases of the National Institutes of Health

National Health and Medical Research Council of Australia

Publisher

American Association for the Advancement of Science (AAAS)