Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome-Reference-Cited by-同舟云学术

Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome

Published:2018-03-09 Issue:21 Volume:3 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Wilson Ariel Molly¹²^ORCID,Shao Zhuo¹,Grenier Vanessa¹^ORCID,Mawambo Gaëlle¹^ORCID,Daudelin Jean-François³,Dejda Agnieszka¹⁴^ORCID,Pilon Frédérique⁴,Popovic Natalija⁴^ORCID,Boulet Salix³,Parinot Célia¹,Oubaha Malika¹^ORCID,Labrecque Nathalie³,de Guire Vincent¹,Laplante Mathieu⁵,Lettre Guillaume⁶^ORCID,Sennlaub Florian⁷^ORCID,Joyal Jean-Sebastien⁸,Meunier Michel²,Sapieha Przemyslaw¹⁴^ORCID

Affiliation:

1. Department of Biochemistry, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.

2. Department of Engineering Physics, École Polytechnique de Montréal, Montreal, Quebec H3T 1J4, Canada.

3. Department of Microbiology, Infectiology and Immunology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.

4. Department of Ophthalmology, Maisonneuve-Rosemont Hospital Research Centre, University of Montreal, Montreal, Quebec H1T 2M4, Canada.

5. Centre de recherche de l’Institut universitaire de cardiologie et de pneumologie de Québec (CRIUCPQ), Université Laval, Faculté de médecine, 2725 Chemin Ste-Foy, Quebec, Quebec G1V 4G5, Canada.

6. Montreal Heart Institute, Université de Montréal, Montreal, Quebec H1T 1C8, Canada.

7. Institut de la Vision, Institut National de la Santé et de la Recherche Médicale, U 968, Paris F-75012, France.

8. Departments of Pediatrics, Ophthalmology, and Pharmacology, Centre Hospitalier Universitaire Ste-Justine Research Center, Université de Montréal, Montreal, Quebec H1T 2M4, Canada.

Abstract

Neuropilin-1–expressing adipose tissue macrophages are critical mediators of protective inflammation during weight gain.

Funder

Canadian Institutes of Health Research

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference50 articles.

1. Prosperity's Plague

2. Obesity is associated with macrophage accumulation in adipose tissue

3. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity