Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation-Reference-Cited by-同舟云学术

Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation

Published:2016-09-16 Issue:3 Volume:1 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Hayashizaki Koji¹,Kimura Motoko Y.¹,Tokoyoda Koji¹²,Hosokawa Hiroyuki¹,Shinoda Kenta¹,Hirahara Kiyoshi¹,Ichikawa Tomomi¹,Onodera Atsushi¹,Hanazawa Asami¹²,Iwamura Chiaki¹,Kakuta Jungo³,Muramoto Kenzo³,Motohashi Shinichiro⁴,Tumes Damon J.¹⁵,Iinuma Tomohisa⁶,Yamamoto Heizaburo⁶,Ikehara Yuzuru⁷,Okamoto Yoshitaka⁶,Nakayama Toshinori¹⁸

Affiliation:

1. Department of Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.

2. Deutsches Rheuma-Forschungszentrum Berlin, Charitéplatz 1, 10117 Berlin, Germany.

3. KAN Research Institute Inc., 6-8-2 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.

4. Department of Medical Immunology, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba 260-8670, Japan.

5. South Australian Health and Medical Research Institute, North Terrace, Adelaide SA 5000, Australia.

6. Department of Otorhinolaryngology, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba 260-8670, Japan.

7. Department of Molecular and Tumor Pathology, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba 260-8670, Japan.

8. Japan Agency for Medical Research and Development (AMED)–Core Research for Evolutionary Medical Science and Technology (CREST), AMED, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.

Abstract

CD69 on activated T cells interacts with Myl9/12 expressed in inflamed airways, establishing tissue inflammation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference53 articles.

1. Molecular characterization of the early activation antigen CD69: A type II membrane glycoprotein related to a family of natural killer cell activation antigens

2. CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

3. The activation antigen CD69

4. Finding a way out: lymphocyte egress from lymphoid organs

5. CD69 Controls the Pathogenesis of Allergic Airway Inflammation

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