SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients-Reference-Cited by-同舟云学术

SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients

Published:2021-05-28 Issue:59 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Geers Daryl¹^ORCID,Shamier Marc C.¹^ORCID,Bogers Susanne¹,den Hartog Gerco²^ORCID,Gommers Lennert¹^ORCID,Nieuwkoop Nella N.¹,Schmitz Katharina S.¹^ORCID,Rijsbergen Laurine C.¹,van Osch Jolieke A. T.¹,Dijkhuizen Emma¹,Smits Gaby²,Comvalius Anouskha¹,van Mourik Djenolan¹,Caniels Tom G.³^ORCID,van Gils Marit J.³^ORCID,Sanders Rogier W.³⁴^ORCID,Oude Munnink Bas B.¹^ORCID,Molenkamp Richard¹^ORCID,de Jager Herbert J.⁵^ORCID,Haagmans Bart L.¹^ORCID,de Swart Rik L.¹^ORCID,Koopmans Marion P. G.¹^ORCID,van Binnendijk Robert S.²^ORCID,de Vries Rory D.¹^ORCID,GeurtsvanKessel Corine H.¹^ORCID

Affiliation:

1. Department of Viroscience, Erasmus MC, Rotterdam, Netherlands.

2. Centre for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven, Netherlands.

3. Department of Medical Microbiology, Amsterdam UMC, Amsterdam, Netherlands.

4. Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA.

5. Department of Occupational Health Services, Erasmus MC, Rotterdam, Netherlands.

Abstract

Infection- or vaccination-induced SARS-CoV-2 S–specific CD4 + T cells are indifferent to the S mutations of variants of concern.

Funder

Bill and Melinda Gates Foundation

Netherlands Organization for Scientific Research

ZonMW