A specific gene-microbe interaction drives the development of Crohn’s disease–like colitis in mice-Reference-Cited by-同舟云学术

A specific gene-microbe interaction drives the development of Crohn’s disease–like colitis in mice

Author:

Caruso R.¹²^ORCID,Mathes T.¹²^ORCID,Martens E. C.³^ORCID,Kamada N.⁴^ORCID,Nusrat A.¹,Inohara N.¹^ORCID,Núñez G.¹²^ORCID

Affiliation:

1. Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

2. Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

3. Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

4. Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Abstract

Combined deficiency of NOD2 and NAPDH oxidase triggers Crohn’s-like disease driven by a mouse pathobiont, Mucispirillum .

Funder

National Institutes of Health

Crohn’s and Colitis Foundation of America

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference73 articles.

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