A subset of follicular helper-like MAIT cells can provide B cell help and support antibody production in the mucosa

Author:

Jensen Owen12ORCID,Trivedi Shubhanshi1ORCID,Meier Jeremy D.34,Fairfax Keke C.2ORCID,Hale J. Scott2ORCID,Leung Daniel T.12ORCID

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.

2. Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT ,USA.

3. Division of Otolaryngology-Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.

4. Primary Children’s Hospital, Salt Lake City, UT, USA.

Abstract

We identify a MAIT cell subset expressing T follicular helper markers and show the ability of MAIT cells to support B cell responses in the mucosa.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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