Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA-Reference-Cited by-同舟云学术

Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA

Published:2021-12-24 Issue:66 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Oh Ji Eun¹²^ORCID,Song Eric¹^ORCID,Moriyama Miyu¹^ORCID,Wong Patrick¹^ORCID,Zhang Sophia¹,Jiang Ruoyi¹^ORCID,Strohmeier Shirin³,Kleinstein Steven H.¹⁴⁵^ORCID,Krammer Florian³^ORCID,Iwasaki Akiko¹⁶⁷^ORCID

Affiliation:

1. Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519, USA.

2. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.

3. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

4. Department of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.

5. Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.

6. Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven CT 06520, USA.

7. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

Abstract

A heterogeneous population of cells secreting mucosal IgA confers protection against influenza virus infection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference36 articles.

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4. IgA Function in Relation to the Intestinal Microbiota

5. Epithelial transcytosis of monomeric IgA and IgG cross-linked through antigen to polymeric IgA. A role for monomeric antibodies in the mucosal immune system;Kaetzel C. S.;J. Immunol.,1994

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