The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity-Reference-Cited by-同舟云学术

The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity

Published:2020-07-03 Issue:49 Volume:5 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Salzer Elisabeth¹²³⁴^ORCID,Zoghi Samaneh¹²³⁵⁶^ORCID,Kiss Máté G.³⁷^ORCID,Kage Frieda⁸⁹^ORCID,Rashkova Christina¹³¹⁰,Stahnke Stephanie⁹^ORCID,Haimel Matthias¹²³^ORCID,Platzer René¹¹,Caldera Michael³^ORCID,Ardy Rico Chandra¹²³^ORCID,Hoeger Birgit¹²³^ORCID,Block Jana¹²³,Medgyesi David¹,Sin Celine³^ORCID,Shahkarami Sepideh⁵¹²¹³,Kain Renate¹⁴,Ziaee Vahid¹⁵¹⁶^ORCID,Hammerl Peter¹⁷,Bock Christoph¹³^ORCID,Menche Jörg³^ORCID,Dupré Loïc¹¹⁸^ORCID,Huppa Johannes B.¹¹^ORCID,Sixt Michael¹⁹,Lomakin Alexis¹²³^ORCID,Rottner Klemens⁸⁹^ORCID,Binder Christoph J.³⁷,Stradal Theresia E. B.⁹^ORCID,Rezaei Nima⁵⁶²⁰^ORCID,Boztug Kaan¹²³⁴¹⁰^ORCID

Affiliation:

1. Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.

2. St. Anna Children’s Cancer Research Institute (CCRI), Vienna, Austria.

3. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

4. St. Anna Children’s Hospital, Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

5. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

6. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

7. Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.

8. Division of Molecular Cell Biology, Zoological Institute, Technische Universität Braunschweig, Braunschweig, Germany.

9. Department of Cell Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.

10. Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.

11. Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

12. Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

13. Medical Genetics Network (MeGeNe), Universal Scientific Education and Research Network (USERN), Tehran, Iran.

14. Department of Pathology, Medical University of Vienna, Vienna, Austria.

15. Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

16. Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.

17. Department of Molecular Biology, University of Salzburg, Salzburg, Austria.

18. Center for Pathophysiology of Toulouse Purpan, INSERM UMR1043, CNRS UMR5282, Paul Sabatier University, Toulouse, France.

19. Institute of Science and Technology Austria, Klosterneuburg, Austria.

20. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.

Abstract

HEM1 deficiency causes heritable autoimmunity and immunodeficiency.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference80 articles.

1. Actin cytoskeletal defects in immunodeficiency

2. Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease

3. A novel primary human immunodeficiency due to deficiency in the WASP-interacting protein WIP

4. Identification of Two Human WAVE/SCAR Homologues as General Actin Regulatory Molecules Which Associate with the Arp2/3 Complex

5. A nucleator arms race: cellular control of actin assembly

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