KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C-Reference-Cited by-同舟云学术

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Published:2017-09 Issue:15 Volume:2 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Naiyer Mohammed M.¹^ORCID,Cassidy Sorcha A.¹²^ORCID,Magri Andrea³⁴^ORCID,Cowton Vanessa³^ORCID,Chen Kevin¹^ORCID,Mansour Salah¹,Kranidioti Hariklia¹^ORCID,Mbiribindi Berenice¹^ORCID,Rettman Pauline¹^ORCID,Harris Scott⁵^ORCID,Fanning Liam J.⁶^ORCID,Mulder Arend⁷^ORCID,Claas Franz H. J.⁷^ORCID,Davidson Andrew D.⁸,Patel Arvind H.³^ORCID,Purbhoo Marco A.²,Khakoo Salim I.¹^ORCID

Affiliation:

1. Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Tremona Road, Southampton S016 6YD, UK.

2. Section of Hepatology, Division of Medicine, Imperial College London, South Wharf Road, London W2 1PG, UK.

3. Medical Research Council–University of Glasgow Centre for Virus Research, Garscube Campus, 464 Bearsden Road, Glasgow G61 1QH, UK.

4. Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.

5. Department of Statistics, Population and Primary Care Medicine, Faculty of Medicine, University of Southampton, Southampton General Hospital, Tremona Road, Southampton S016 6YD, UK.

6. Department of Medicine, University College Cork, Cork, Ireland.

7. Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, PO Box 9600, 2300RC Leiden, Netherlands.

8. School of Cellular and Molecular Medicine, Biomedical Sciences Building, University of Bristol, Bristol BS8 1TD, UK.

Abstract

KIR2DS2, an activating natural killer cell receptor, recognizes conserved peptides derived from the RNA helicases of pathogenic flaviviruses.

Funder

Wellcome Trust

Medical Research Council

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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