Tissue-resident CD8 + T cells drive age-associated chronic lung sequelae after viral pneumonia-Reference-Cited by-同舟云学术

Tissue-resident CD8 + T cells drive age-associated chronic lung sequelae after viral pneumonia

Published:2020-11-13 Issue:53 Volume:5 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Goplen Nick P.¹²^ORCID,Wu Yue³^ORCID,Son Young Min¹^ORCID,Li Chaofan¹,Wang Zheng¹^ORCID,Cheon In Su¹,Jiang Li¹^ORCID,Zhu Bibo¹,Ayasoufi Katayoun³,Chini Eduardo N.²⁴,Johnson Aaron J.³^ORCID,Vassallo Robert¹^ORCID,Limper Andrew H.¹,Zhang Nu⁵^ORCID,Sun Jie¹²³^ORCID

Affiliation:

1. Division of Pulmonary and Critical Medicine, Department of Medicine, Mayo Clinic, Rochester, MN 55905, USA.

2. The Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN 55905, USA.

3. Department of Immunology, Mayo Clinic, Rochester, MN 55905, USA.

4. Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA.

5. Long School of Medicine, Departments of Microbiology, Immunology, and Molecular Genetics, University of Texas Health San Antonio, San Antonio, TX 78229, USA.

Abstract

Age-associated T RM cell malfunction supports chronic lung inflammation and tissue fibrosis after respiratory viral infection.

Funder

National Institutes of Health

National Institute on Aging

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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