Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 + T cells-Reference-Cited by-同舟云学术

Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8 + T cells

Published:2020-09-18 Issue:51 Volume:5 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Perez-Shibayama Christian¹^ORCID,Islander Ulrika²^ORCID,Lütge Mechthild¹^ORCID,Cheng Hung-Wei¹^ORCID,Onder Lucas¹,Ring Sandra S.¹,De Martin Angelina¹,Novkovic Mario¹^ORCID,Colston Julia³,Gil-Cruz Cristina¹^ORCID,Ludewig Burkhard¹⁴^ORCID

Affiliation:

1. Institute of Immunobiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.

2. Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg, Sweden.

3. Department of Medicine, Peter Medawar Building for Pathogen Research, University of Oxford, Oxford, UK.

4. Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.

Abstract

Programming of lymph node fibroblastic reticular cells by type I interferons is needed for effective antiviral CD8 + T cell responses.

Funder

Swiss National Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference68 articles.

1. Immunology Taught by Viruses

2. Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

3. Control of adaptive immunity by the innate immune system

4. Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence

5. Fibroblastic reticular cells at the nexus of innate and adaptive immune responses

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