Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis-Reference-Cited by-同舟云学术

Clonal expansion of vaccine-elicited T cells is independent of aerobic glycolysis

Published:2018-09-21 Issue:27 Volume:3 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Klarquist Jared¹^ORCID,Chitrakar Alisha¹^ORCID,Pennock Nathan D.¹^ORCID,Kilgore Augustus M.¹^ORCID,Blain Trevor¹,Zheng Connie²^ORCID,Danhorn Thomas³^ORCID,Walton Kendra³^ORCID,Jiang Li⁴,Sun Jie⁴,Hunter Christopher A.⁵,D’Alessandro Angelo²,Kedl Ross M.¹^ORCID

Affiliation:

1. Department of Immunology and Microbiology, University of Colorado Denver, Denver, CO 80045, USA.

2. Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Denver, CO 80045, USA.

3. Center for Genes, Environment and Health, National Jewish Health, Denver, CO 80206, USA.

4. Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA.

5. University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.

Abstract

T cell responses to subunit vaccination require both IL-27 and IL-15 to support an aerobic glycolysis–independent metabolic program.

Funder

NIH Office of the Director

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference74 articles.

1. Duration of Humoral Immunity to Common Viral and Vaccine Antigens

2. Immunity and immunological memory following smallpox vaccination;Amanna I. J.;Immunol. Rev.,2006

3. C. M. Bosio M. MacLeod P. Marrack R. M. Kedl Utility of mouse models in vaccine design and development in Vaccinology: Principles and Practice W. J. W. Morrow N. A. Sheikh C. S. Schmidt D. H. Davies Eds. (Wiley-Blackwell 2012) pp. 94–109.

4. Inflammatory cytokines as a third signal for T cell activation

5. Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor

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