Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection-Reference-Cited by-同舟云学术

Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection

Published:2019-02-08 Issue:32 Volume:4 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Cheng Yang¹^ORCID,Zhu Yuan O.²^ORCID,Becht Etienne¹,Aw Pauline²^ORCID,Chen Jinmiao¹^ORCID,Poidinger Michael¹^ORCID,de Sessions Paola Flórez²,Hibberd Martin Lloyd²³^ORCID,Bertoletti Antonio¹⁴,Lim Seng Gee⁵^ORCID,Newell Evan W.¹⁶^ORCID

Affiliation:

1. Singapore Immunology Network, Agency for Science, Technology and Research, Singapore.

2. Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore.

3. Emerging Infectious Disease, Department of Pathogen Molecular Biology, London School of Hygiene & Tropical Medicine, London, UK.

4. Emerging Infectious Disease Program, Duke-NUS Medical School, Singapore.

5. Division of Gastroenterology & Hepatology, National University Health System, Singapore.

6. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Abstract

Comprehensive epitope mapping and high-dimensional analyses uncover complex relationships of virus-specific memory T cells in CHB.

Funder

Agency for Science, Technology and Research

National Medical Research Council

Singapore Immunology Network

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference79 articles.

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2. Immunology of hepatitis B virus and hepatitis C virus infection

3. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

4. The immune tolerant phase of chronic HBV infection: new perspectives on an old concept

5. New perspectives on the hepatitis B virus life cycle in the human liver

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