Adipocytes sensitize melanoma cells to environmental TGF-β cues by repressing the expression of miR-211-Reference-Cited by-同舟云学术

Adipocytes sensitize melanoma cells to environmental TGF-β cues by repressing the expression of miR-211

Published:2019-07-23 Issue:591 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Golan Tamar¹^ORCID,Parikh Roma¹,Jacob Etai²³⁴⁵,Vaknine Hananya⁶,Zemser-Werner Valentina⁷^ORCID,Hershkovitz Dov⁷⁸^ORCID,Malcov Hagar¹,Leibou Stav¹,Reichman Hadar¹^ORCID,Sheinboim Danna¹,Percik Ruth⁸⁹,Amar Sarah⁶^ORCID,Brenner Ronen⁶^ORCID,Greenberger Shoshana¹⁰^ORCID,Kung Andrew¹¹^ORCID,Khaled Mehdi¹²^ORCID,Levy Carmit¹^ORCID

Affiliation:

1. Department of Human Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

2. The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel.

3. Department of Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.

4. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

5. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

6. Institute of Pathology, E. Wolfson Medical Center, Holon 58100, Israel.

7. Institute of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv 6423906, Israel.

8. Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

9. Institute of Endocrinology, Chaim Sheba Medical Center, Tel Hashomer, Israel.

10. Department of Dermatology, Sheba Medical Center, Tel Hashomer 52621, Israel.

11. Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

12. INSERM 1186, Gustave Roussy, Université Paris-Saclay, Villejuif 94805, France.

Abstract

Fat cells secrete cytokines that enhance pro-metastatic TGF-β signaling in melanoma cells.

Funder

Israel Science Foundation , ISF

Melanoma Research Alliance, MRA

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference79 articles.

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