A switch in G protein coupling for type 1 corticotropin-releasing factor receptors promotes excitability in epileptic brains-Reference-Cited by-同舟云学术

A switch in G protein coupling for type 1 corticotropin-releasing factor receptors promotes excitability in epileptic brains

Published:2016-06-14 Issue:432 Volume:9 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Narla Chakravarthi¹²,Scidmore Tanner¹²,Jeong Jaymin¹³,Everest Michelle¹,Chidiac Peter²⁴,Poulter Michael O.¹²³

Affiliation:

1. Molecular Medicine Research Group, Robarts Research Institute, Schulich School of Medicine, University of Western Ontario, London, Ontario N6A 5K8, Canada.

2. Department of Physiology and Pharmacology, Schulich School of Medicine, University of Western Ontario, London, Ontario N6A 3K7, Canada.

3. Graduate Program in Neuroscience, Schulich School of Medicine, University of Western Ontario, London, Ontario N6A 5K8, Canada.

4. Department of Biology, Schulich School of Medicine, University of Western Ontario, London, Ontario N6A 3K7, Canada.

Abstract

A stress-induced neuropeptide enhances, rather than suppresses, neuronal activity in the epileptic brain.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council

Ontario Graduate Scholarship

Western University Graduate Research Scholarship

Schulich School of Medicine

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference52 articles.

1. Distribution of Seizure Precipitants Among Epilepsy Syndromes

2. The global burden and stigma of epilepsy

3. The impact of generalized anxiety disorder and stressful life events on risk for major depressive episodes

4. Suicide in the epilepsies: A meta-analytic investigation of 29 cohorts

5. Seizure Frequency and Cortisol and Dehydroepiandrosterone Sulfate (DHEAS) Levels in Women with Epilepsy Receiving Antiepileptic Drug Treatment

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