New Regulators of Wnt/β-Catenin Signaling Revealed by Integrative Molecular Screening-Reference-Cited by-同舟云学术

New Regulators of Wnt/β-Catenin Signaling Revealed by Integrative Molecular Screening

Published:2008-11-11 Issue:45 Volume:1 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Major Michael B.¹,Roberts Brian S.²,Berndt Jason D.¹,Marine Shane³,Anastas Jamie¹,Chung Namjin³,Ferrer Marc³,Yi XianHua⁴,Stoick-Cooper Cristi L.¹,von Haller Priska D.⁵,Kategaya Lorna¹,Chien Andy¹,Angers Stephane⁶,MacCoss Michael⁴,Cleary Michele A.²,Arthur William T.²,Moon Randall T.¹

Affiliation:

1. Howard Hughes Medical Institute, Department of Pharmacology, and Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Box 357370, Seattle, WA 98195, USA.

2. Rosetta Inpharmatics, LLC, Merck & Co Inc., 401 Terry Avenue N, Seattle, WA 98109, USA.

3. Merck Research Labs, Department of Automated Biotechnology, North Wales, PA 19454, USA.

4. Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.

5. Proteomics Resource, University of Washington, Seattle, WA 98109, USA.

6. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada M5S 3M2.

Abstract

Integration of protein-protein interaction networks and human genome-wide RNAi screens produces mechanistic insight into Wnt/β-catenin signaling.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference36 articles.

1. Identification and characterization of the familial adenomatous polyposis coli gene

2. Identification of FAP Locus Genes from Chromosome 5q21

3. Wnt signaling in the intestinal epithelium: from endoderm to cancer

4. THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE

5. WNT and β-catenin signalling: diseases and therapies

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