Hedgehog-Stimulated Chemotaxis Is Mediated by Smoothened Located Outside the Primary Cilium-Reference-Cited by-同舟云学术

Hedgehog-Stimulated Chemotaxis Is Mediated by Smoothened Located Outside the Primary Cilium

Published:2012-08-21 Issue:238 Volume:5 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Bijlsma Maarten F.¹²,Damhofer Helene²,Roelink Henk¹

Affiliation:

1. Department of Molecular and Cell Biology, University of California, Berkeley, 16 Barker Hall, 3204, Berkeley, CA 94720, USA.

2. Laboratory for Experimental Oncology and Radiobiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, Netherlands.

Abstract

Hedgehog stimulates a chemotactic or transcriptional response depending on the intracellular trafficking of the co-receptor Smoothened.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference44 articles.

1. Hedgehog signaling in animal development: paradigms and principles

2. Vertebrate Smoothened functions at the primary cilium

3. Cilia and Developmental Signaling

4. Patched1 Regulates Hedgehog Signaling at the Primary Cilium

5. Smoothened Adopts Multiple Active and Inactive Conformations Capable of Trafficking to the Primary Cilium

Cited by 65 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A cell-autonomous role for primary cilium-mediated signaling in long-range commissural axon guidance;Development;2024-09-01

2. Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development;Scientific Reports;2023-07-29

3. Sonic Hedgehog Signaling Pathway: A Role in Pain Processing;Neurochemical Research;2023-02-04

4. Establishing Hedgehog Gradients during Neural Development;Cells;2023-01-05

5. Unraveling the actin cytoskeleton in the malignant transformation of cholangiocyte biology;Translational Oncology;2022-12