Noncanonical NF-κB Activation by the Oncoprotein Tio Occurs Through a Nonconserved TRAF3-Binding Motif-Reference-Cited by-同舟云学术

Noncanonical NF-κB Activation by the Oncoprotein Tio Occurs Through a Nonconserved TRAF3-Binding Motif

Published:2013-04-23 Issue:272 Volume:6 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

de Jong Sarah Jill¹,Albrecht Jens-Christian¹,Giehler Fabian²,Kieser Arnd²,Sticht Heinrich³,Biesinger Brigitte¹

Affiliation:

1. Institut für Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany.

2. Abteilung Genvektoren, Helmholtz Zentrum München–Deutsches Forschungszentrum für Gesundheit und Umwelt, D-81377 München, Germany.

3. Institutfür Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany.

Abstract

The viral protein Tio specifically stimulates noncanonical nuclear factor κB signaling through a distinct interaction with the adaptor and ubiquitin ligase TRAF3.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference47 articles.

1. Regulation and Function of NF-κB Transcription Factors in the Immune System

2. Oncogenic Activation of NF- B

3. Aberrant NF-κB signaling in lymphoma: mechanisms, consequences, and therapeutic implications

4. NF-κB signaling modulation by EBV and KSHV

5. HTLV-1 and Adult T-Cell Leukemia: Insights into Viral Transformation of Cells 30 Years After Virus Discovery

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